D3-5
(Vitamin D3 / Cholecalciferol)

WHAT DOES VITAMIN D DO?

Vitamin D is essential for normal bone growth and development, and to maintain bone density. It is also necessary for utilization of both calcium and phosphorus. Vitamin D acts as a hormone and increases re-absorption of calcium and phosphorus by the kidneys and increased bone turnover. Vitamin D may also increase the calcium around damaged joints in persons with gout and rheumatoid arthritis. Vitamin D3 has been used to prevent and treat various cancers, including breast and prostate. Scientific evidence supports the concept that vitamin D likely plays an important role in controlling auto-immunity and MS.

 

VITAMIN D AND CHRONIC DISEASE

Studies done by P. Goldberg in 1974 show that the conspicuous high prevalence of MS in areas of the world that receive a relatively low amount of sunlight may indeed be linked to vitamin D deficiency. In the early 80s, science recognized that immune cells carry a receptor for the active hormone of vitamin D and that this hormone likely regulates immune functions. This led to ongoing research efforts which continue to uncover a number of important ways in which vitamin D hormone affects the immune system, and subsequent studies show that injections of vitamin D hormone could protect against or arrest MS, type 1 diabetes, rheumatoid arthritis, and lupus. Other studies done in 1999 confirmed that supplementation with vitamin D was associated with a decreased risk of type 1 diabetes.

 

WHO NEEDS VITAMIN D SUPPLEMENTATION?

People with adequate access to sunlight usually do not need dietary vitamin D because ultraviolet light converts 7-dehydrocholesterol (abundant in skin) to vitamin D3 (cholecalciferol). A dominance of indoor jobs, fears of skin cancer and the use of sunscreens have reduced exposure times to sunlight such that, even in summer, many people do not get anywhere near the required vitamin D intake from sunlight. Chronic vitamin D deficiency exists in populations which live in low sunlight climates. 

Because the use of steroidal drugs (in MS treatment) depletes vitamin D supplies and inhibits absorption, supplementation is quite beneficial. Anyone suffering from immune or autoimmune disorders can benefit from vitamin D supplementation.

Testing done (1992-1998) have revealed the following immune-regulating actions for vitamin D hormone:

 

VITAMIN D DEFICIENCY

Vitamin D deficiency causes rickets in children, exacerbates osteoporosis and causes osteomalacia in adults. Vitamin D must be taken with adequate amounts of both calcium and magnesium supplementation. When calcium levels are low (due to insufficient vitamin D and calcium intake), the body activates the parathyroid gland, which produces PTH (parathyroid hormone). This hormone kick starts vitamin D hormone production and assists removal of calcium from the bones to be used in more important functions such as neutralizing body acidity.

 

NATURAL SOURCES OF VITAMIN D

Very few foods naturally contain vitamin D. Fatty fish such as salmon and cod, vitamin D-fortified milk, cereals, and multivitamin supplements are the major sources of vitamin D. The main source of vitamin D is the sun and in hot climates such an intake is readily possible if an individual spends a reasonable amount of time in the sun. However, in colder climates, like those of Canada, northern USA and northwest Europe, it is almost impossible to average 4,000 IU per day because for at least six months of the year, intake from the sun is negligible at best. Even during the few hot summer months, an individual would have to spend considerable time in the sun to achieve the required intake.

 

DIETARY FACTORS THAT AFFECT VITAMIN D LEVELS

Original man's diet was dominated by fruits, vegetables, and lean wild meats which have a low saturated fat content. The main foods introduced by agriculture are grains, dairy products, and meat from domesticated animals which has a very high saturated fat content. 

Grains contain phytate or phytic acid, which counters the action of vitamin D. The only common grain with a very low phytate content is rice. 

In 1991, studies showed that part of the bovine albumin protein or milk is a molecular mimic of the vitamin D receptor. An immune reaction against that milk protein can potentially result in an autoimmune reaction against the vitamin D receptor, which would significantly lower the effectiveness of vitamin D hormone to bind with a variety of cells, including immune cells. 

Proteins from various foods introduced by the agricultural revolution (gluten, dairy, legumes) result in autoimmune reactions by increasing intestinal permeability and by mimicking infectious and self-antigens. The great increase in the consumption of saturated fat also contributes to an increase in inflammatory reactions. Food-driven autoimmune reactions occur almost on a daily basis. They have a significant cumulative effect and result in harmless auto-immunity becoming problematic autoimmune disease in genetically susceptible people. 

Alcohol consumption also interferes with vitamin D metabolism.

 

VITAMIN D TOXICITY

Vitamin D toxicity effects include excessive absorption of calcium from the intestine and resorption of calcium from bone. This results in deposits of calcium and phosphorus in soft tissues all over the body, with particular damage to the heart, blood vessels, and kidneys. 2,000 IU daily poisons children, and especially sensitive children have been intoxicated with less than half of that. Studies done in 1999 by R. Vieth shows that 10,000 IU/day produce no observed adverse effects in adults and concluded that 10,000 IU/day is safe (assuming no hypersensitivity exists).

 

HOW TO TAKE VITAMIN D SUPPLEMENTS

Because vitamin D is a fat-soluble vitamin, it is more effectively utilized when taken in divided doses with fat-containing, low fiber meals.

 

VITAMIN D REQUIREMENTS

Vitamin D requirements depend on sun exposure, skin color, and dietary factors. Recommendations range from 600 IU per day for adult Canadians to 400 IU for Canadian infants. Treatment of vitamin D deficiency in adults can be corrected by 50,000 IU of vitamin D once a week for 8 weeks followed by a multivitamin containing 400 IU/day.

 

D3-5 (5,000 IU) - 250 caps
$30 (US)

D3-50 (50,000 IU) - 100 caps
$35(US)



To find out more,
Call The Wolfe Clinic
TOLL FREE
1-800-592-9653

If our 1-800 number

is not available from your area,

please call us at

250-765-1824

 

SEND THIS PAGE TO A FRIEND: If you know someone who could benefit from the information on this page, please forward it to them by clicking FILE, SEND (on the toolbar in your web browser).

Updated January 01, 2007

Disclaimer

*Under current legislation, The Wolfe Clinic is not permitted to make claims to consumers in support of health benefits derived from foods. This means we cannot make specific statements as to how food-based, non-drug products may help to prevent or treat diseases or our government will attempt to re-classify that food as a drug. Taking natural products should be a decision based on personal research and understanding of the role food-derived antioxidants and enzymes play in health and wellbeing.

The information provided within this site is for informational purposes only and is not intended as a substitute for advice from a physician or other health care professional, and should not be used for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. A health care professional should be consulted before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. Do not discontinue any other medical treatments without first consulting your doctor.