LIBIDO ENHANCING
& SEXUAL PERFORMANCE STUDIES
Effect
of Lepidium meyenii (Maca) on sexual desire and its absent
relationship with serum testosterone levels in adult healthy
men. Gonzales GF, Cordova A, Vega K,
Chung A, Villena A, Gonez C, Castillo S. Instituto de
Investigaciones de la Altura, and Department of Biological and
Physiological Sciences (Faculty of Sciences and Philosophy),
Universidad Peruana Cayetano Heredia, Lima, Peru. Andrologia 2002 Dec; 34(6): 367-72
This study was a
12-week double blind placebo-controlled, randomized, parallel
trial in which active treatment with different doses of
Gelatinized Maca was compared with placebo. The study aimed to
demonstrate if effect of Maca on subjective report of sexual
desire was because of effect on mood or serum testosterone
levels.
Men aged 21-56
years received Maca in one of two doses: 1,500 mg or 3,000 mg
or placebo. Self-perception on sexual desire, score for
Hamilton test for depression, and Hamilton test for anxiety
were measured at 4, 8 and 12 weeks of treatment. An
improvement in sexual desire was observed with Maca since 8
weeks of treatment. Serum testosterone and oestradiol levels
were not different in men treated with Maca and in those
treated with placebo (P=NS).
Logistic
regression analysis showed that Maca has an independent effect
on sexual desire at 8 and 12 weeks of treatment, and this
effect is not because of changes in either Hamilton scores for
depression or anxiety or serum testosterone and oestradiol
levels. In conclusion, treatment with Maca improved sexual
desire.
PMID: 12472620 [PubMed - in process]
Effect
of a Lipidic Extract from Lepidium meyenii on Sexual
Behavior in Mice and Rats. Zheng BL,
He K, Hyungchan C, et al. Urology
2000; 55:598-602
This clinical
study evaluates the effect of a purified lipidic extract of
Lepidium meyenii (Maca) in the sexual behaviour of mice and
rats. Oral administration of Maca extract enhanced the sexual
function of the mice and rats, as evidenced by an increase in
the number of complete intromissions and the number of
sperm-positive females in normal mice, and a decrease in the
LPE in male rats with erectile dysfunction. The present study
reveals for the first time an aphrodisiac activity of L.
meyenii, an Andean mountain herb.
PMID: 10736519 [PubMed
- indexed for MEDLINE]
Lepidium meyenii Walp. improves sexual behaviour in male rats
independently from its action on spontaneous locomotor
activity. Cicero AF, Bandieri E,
Arletti R. Biomedical Sciences Department, Pharmacology
Section, University of Modena and Reggio nell'Emilia, Via G.
Campi, 287, 41100, Modena, Italy. Journal of Ethnopharmacol 2001 May; 75 (2-3): 225-9
Lepidium meyenii Walpers (Maca) is traditionally employed in
the Andean region for its supposed properties to improve
energy and fertility. The aim of this study was to evaluate
the effect of acute and chronic Maca pulverized root oral
administration on rat sexual behaviour.
Sixty male
sexually experienced rats (20 group) were daily treated for 15
days with Maca 15 mg kg(-1), Maca 75 mg kg(-1) or saline 0.5
ml kg(-1). An activity cage test was carried out to evaluate
if Maca-induced locomotion changes could indirectly improve
rat sexual performances. It was concluded that both acute and
chronic Maca oral administration significantly improve sexual
performance parameters in male rats.
PMID: 11297856 [PubMed - indexed for
MEDLINE]
Effect
of Lepidium meyenii (Maca), a root with aphrodisiac and
fertility-enhancing properties, on serum reproductive hormone
levels in adult healthy men. Gonzales GF, Cordova A, Vega K, Chung A, Villena A, Gonez C.
Instituto de Investigaciones de la Altura, and Department of
Biological and Physiological Sciences (Faculty of Sciences and
Philosophy), Universidad Peruana Cayetano Heredia, PO 1843,
Lima, Peru. Journal of Endocrinology
2003 Jan; 176 (1): 163-8
This
study was a 12-week double-blind, placebo-controlled,
randomized, parallel trial in which active treatment with
different doses of Gelatinized Maca was compared with a
placebo. The study aimed to test the hypothesis that Maca has
no effect on serum reproductive hormone levels in apparently
healthy men when administered in doses used for aphrodisiac
and/or fertility-enhancing properties. Men aged between 21 and
56 Years received 1,500 mg or 3,000 mg Maca. Serum levels of
luteinizing hormone, follicle-stimulating hormone, prolactin,
17-alpha hydroxyprogesterone, testosterone and 17-beta
estradiol were measured before and at 2, 4, 8 and 12 weeks of
treatment with placebo or Maca.
Data
showed that compared with placebo Maca had no effect on any of
the hormones studied nor did the hormones show any changes
over time. Multiple regression analysis showed that serum
testosterone levels were not affected by treatment with Maca
at any of the times studied (P=NS). In conclusion, treatment
with Maca does not affect serum reproductive hormone levels.
PMID: 12525260 [PubMed
- in process]
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